Tycho Brahe didn’t get to the toilet in time
Famous as an alchemist and astronomer, Brahe’s pioneering observations of the motion of planets opened the way for Sir Isaac Newton to develop the theory of gravity.
Unfortunately, brilliance and common sense do not always go hand in hand, the way of his death being the case. Recognized for having a weak bladder and knowing that it was very bad to leave the banquet table before the end of the festivities, Brahe still neglected to relieve himself before dinner. To make matters worse, he was known to drink excessively, and this banquet in particular was no exception. Too polite to ask to be excused, his bladder was put to the test, causing an agonizing death (11 days). It is now debated whether he has died of an exploded bladder, hyponatraemia (low blood sodium levels) or mercury poisoning.
Note: This is very similar to an event in which a lady recently passed away in a contest called “Hold Your Wee for a Wii“. She died of hyponatremia.