There is realistic evidence of neurological problems around Celiac disease (CD) possibly those well treated over a gluten-free diet should go through periodic neurological screening. Peripheral neuropathy is found in almost 50 % of people with CD. Previously, brain complications in Celiac illness were reported to be of up to 36% or more than a next. Some unexplained neurological danger is present but not recognized by the affected person or their doctor in several patients and some have a few problems. Unfortunately, since mind imaging is not routinely performed or recommended in individuals who are newly diagnosed we have a tendency really know how high these kinds of numbers may be really be. Additional staggering is the fact that we are continue to learning about people who fail to match diagnostic criteria for Celiac disease but are being discovered to have gluten related brain problems that respond to a gluten-free diet.
There are many brain problems that in undiagnosed together with untreated Celiac disease although include neuropathy, balance issues (ataxia), seizures, MS-like signs or symptoms, headaches, memory impairment, major depression and anxiety, inattention (ADD/ADHD), schizophrenia, dementia, muscle weak point, childhood developmental delay, autism (Asperger’s). The sad reality is that many patients have slow downs in diagnosis that end in delayed treatment and weak response even while adopting a new strict gluten free diet program. The average delay of examination in adults is between 11 and thirteen years. Dr. Hadjivassiliou, a neurologist in britain who is considered the world’s professional in gluten related brain problems has communicated for me by e-mail and prepared that responses to a gluten-free diet may take five a number of if the neurological condition has become longstanding complete recovery will not be likely.
The symptoms of damaged nerves are paresthesia (numbness) or maybe dysthesia (burning, tingling, heaviness, “pins and needles” sensation”). Many of my patients in addition describe hypersensitivity of their pores and skin such that they do not like surroundings blowing on them or youngsters or spouses against their particular skin. Some admit to be able to “bug crawling” sensation on the skin, something called vermiculation in medical terms although rarely asked about or granted much thought by most physicians. Odd muscle movements underneath the skin that some phone a “bag of worms” medically known as fasiculations may also be very common but dismissed by many people doctors. My wife, a physician having Celiac disease, actually got these occur while having an EMG (electromyleograph, tracking of muscle activity by simply placing needle electrode in to the muscle) exam by an adult neurologist. Despite observing these kinds of occurring visually and the screen showing “static like noise” the neurologist dismissed these individuals as “normal”.
Many people with Celiac disease also provide what the radiologists and neurologists call “UBO’s” on MRI exams of the brain. All these unidentified bright objects (think UFO) are white places that show up on images on the brain. When found in selected locations of the brain they are really highly suggestive of ms (multiple scarring spots inside brain). However, though a lot of people with CD have MICROSOFT like signs or symptoms and these symptoms often respond to a gluten free diet when started off early enough, the UBO’s seen on MRI on the brain are typically not inside classic areas of MS. Rather it is common to find them around areas of the brain associated with migraine headaches or balance difficulty (ataxia).
Some are seen in kids associated with strange seizure issues even without obvious intestinal signs or symptoms. A classic specific syndrome is incredibly well recognized associated with epilepsy both in children and adults who have calcifications within their brain that can be detected by simply CT scan or MRI. Epilepsy is well written about but the studies are difficult enough that there is not a good opinion regarding the risk and suggested screening of all children having epilepsy.
Personally and appropriately I have observed all of the brain complications of Celiac illness and most of them I have in addition noted around patients in whom I have not had the capacity to confirm CD but with what I believe are purpose signs and/or genetic exposure to possible gluten sensitivity. I have people with MS-like symptoms, serious unexplained neuropathy, headaches, consideration difficulties, autistic behaviors together with developmental delays who have taken care of immediately gluten-free diet but if they’d listened to doctors who preserved such a “restrictive, expensive, tricky to follow” diet should simply be “imposed” on those with a new established diagnosis of Celiac illness.
If you have neurological issues get testing for Celiac disease before starting a gluten-free diet. If you test unfavorable for CD, make sure these people test you for the comprehensive HLA DQ genetics which includes the high-risk white blood vessels cell patterns DQ2 together with DQ8 for Celiac illness AND get blood tests offering IgG and IgA gliadin antibodies. If your blood checks, including gliadin IgA together with IgG antibodies, are unfavorable or normal then think about stool testing for gliadin antibodies in the stool ($99, http://www.enterolab.com).
The evidence is constantly on the accumulate, though often dismissed or missed, that gluten is toxic to some householder’s brains, even if they do not include CD. If you do have Celiac disease it is likely you already have brain problems and may be at an increased risk despite being on a gluten-free diet. Borrowing from the outdated advertisement against drug abuse “this is your brain on drugs” maybe we should be getting the term out “this is your mind on gluten”. Despite your own test results, consider a tryout of gluten-free diet when you have your testing done when you have unexplained or unresponsive brain problems. You owe to your mind. Like my seven-year-old daughter said to one of our friends, “maybe you should lay off the gluten”.